1992 - 1996 Ph.D. in Neurobiology from the Feinberg Graduate School, Weizmann Institute of Science.
1990 - 1991 M.Sc. in Neurobiology from the Feinberg Graduate School, Weizmann Institute of Science.
1986 - 1989 B.Sc. in biology from Tel-Aviv University, Tel-Aviv, Israel.
November 2000 present Senior lecturer in the Center for Brain and Behavior, Haifa University.
1998 - 2000 Research Associate in the department of Neurophysiology, N.I.M.R., London (Royal Society Fellow).
1996 -1998 Post doctorate research in Prof. Bliss's laboratory in the N.I.M.R., London (EMBO long-term Fellow).
We are interested in biological mechanisms of learning and memory. We aim to understand how memories are being formed and maintained and how memories are faded over time (forgetting).
We are using a combination of biological techniques including molecular biology, biochemistry, cellular imaging, electrophysiology, neuroanatomy and behavior in order to understand the molecular and cellular mechanisms of memory formation and consolidation. Recently, we found the involvement of specific proteins in memory consolidation (e.g. elongation factor-2 and MAPK). We try to understand the specific role of these proteins in learning processes. The research in the laboratory contributes to the growing understanding of how memories are being formed in the normal brain. In addition, the research may explain the biological mechanisms of memory and learning deficits in the case of aging and diseases.
Rosenblum K., Dudai Y. and Richter-Levine G. (1996) LTP increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor in the rat dentate gyrus in vivo. Proc. Natl. Acad. Sci. USA. 93 10457-10460.
Rosenblum K., Berman D., Hazvi S., and Dudai Y. (1997) NMDA receptor and the tyrosine phsophorylation of its 2B subunit in taste learning in the rat insular cortex. Journal of Neuroscience 17 (13) 5129-5135.
Jones M., French P., Bliss TVP and Rosenblum K (1999). Molecular mechanisms of LTP in the insular cortex. Journal of Neuroscience 19 RC36 1-8.
Rosenblum K., Futter M., Jones M., Hulme ED., and Bliss TVP (2000). ERKI/II regulation by the muscarinic acetylcholine receptors in neurones. Journal of Neuroscience 20 (3) 977-985.
Rosenblum K., Futter M., Voss K., Skehel PA., French P., Obosi L and Bliss TVP (2002). The role of ERKI/II in late phase LTP. Journal of Neuroscience 22 (13) 5432-41.
Hanoch Kapzan (MD)